What is tramadol
Tramadol Side Effects

Kinds of Interactions with Tramadol use

There are many kinds of interactions with tramadol use that have been identified and it is important for every patient to be familiar with these interactions. Actually the use of tramadol is contraindicated with acute alcohol intoxication that shows depressed vital signs. Some may also involve changes in oneís metabolism. Take for example; carbamazepine lessens the analgesic effect of tramadol by increasing the metabolism.

Some of the kinds of interactions with tramadol use may happen once you take tramadol withKinds of Interactions with Tramadol use MAOIs like carbex, eldepryl, marplan, nardil and parnate. Tramadol is also known to interact with some of these medications:

ïAlcohol or medicines with alcohol






ïNarcotic pain relievers

ïDrugs used to aid sleep

ïMAO inhibitors

ïPsychiatric medicine


These are just some of the medicines that pose different kinds of interactions with tramadol use. There could be more medications that may possibly interact with tramadol so please ask your doctor about it.

Also, the potential for abuse and dependence with tramadol is low. But there are still cases that have been reported to show dependence and withdrawal for long-term tramadol use. Some experts have received reports of a withdrawal syndrome with tramadol so it is crucial to monitor patients on long-term treatment of tramadol in order to prevent abrupt cessation.

Prescription of tramadol is especially helpful if the pain management for some patients has not responded to simple analgesics and in which NSAIDs are contraindicated. So in order to lessen adverse effects, patients and their needs must be properly considered and the patientís medication history should be properly reviewed. It is important that patients should give their doctors a list of the medicines, herbs, non-prescription drugs or dietary supplements they used or currently using. Patients should also inform their doctor if they smoke, drink or use illegal drugs as these may possibly interact with tramadol.

Seizures can also happen to some patients who are taking tramadol. The risk of a seizure is greater if you are suffering from any of these conditions: a history of drug or alcohol addiction, history of epilepsy or other seizure disorder, head injury, metabolic disorder and many others. It is therefore crucial that you inform your doctor about your individual risk of having a seizure while taking tramadol. You may also need a tramadol dose adjustment or special tests if you are suffering from a kidney disease, liver disease, stomach disorder, and a history of depression, mental illness or with suicidal tendencies.

And lastly, tramadol is not yet known whether it can harm an unborn baby. Tramadol may lead to serious or fatal side effects to a newborn child if the mother uses the medication during pregnancy or during labor. So a pregnant woman must tell a doctor her condition or planning to get pregnant while using tramadol. It is also possible that tramadol can pass into breast milk and may harm a nursing baby. And of course, tramadol should not be administered to children younger than 18 years old.

Patients taking tramadol must be regularly monitored especially during the early phase of therapy. Those suffering from chronic pain must also be monitored during dose titration and where there is dose escalation. Adverse reaction with tramadol may be common to patients hence they must be given proper guidance and advice regarding the proper action should reactions take place.

In particular, the potential for serious drug interactions should never be underestimated. Doctors must be very vigilant in their patientís condition as there are cases when the mechanism of interaction is very unclear hence the patientís condition should be closely monitored. Patients should never worry on alleviating their pain if they know the kinds of interactions with Tramadol use.